Champions attacking the attached realm are considered monsters for each round of combat.
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TSR
Wizards of the Coast
When an attacking champion is pushed forward to attack the realm with The Pristine Tower attached that champion becomes a monster champion. A non-monster champion looses the ability to play icon related support cards of its former type. i.e. regents can't use blood abilities, wizards can't use wizard spells, ect. monsters are unaffected by this, being monsters to start with.
The Pristine Tower effectively changes the attacking champions icon to that a monster for the duration of the battle, making the champion subject to all cards that target monsters. The attacker returns to its normal icon type once the round of battle is ended.
One of the best cards to use with the Pristine Tower is the artifact The Heartwood Spear (318/3rd) if you are using a Dark Sun theme. The Pristine Tower works very well with another Dark Sun holding, Black Waters (98/4th). Which would end any battle at The Pristine Tower before it even began.
On the whole, The Pristine Tower can cause many interesting card plays but really doesn't have the umpf to make the cut in most tournament decks. This card can be quite fun if you have designed your deck around killing monsters, but it won't win you a lot of games.